{"id":3049,"date":"2023-03-23T06:23:40","date_gmt":"2023-03-23T06:23:40","guid":{"rendered":"https:\/\/medshop4unew.nbgsurgical.com\/?post_type=product&#038;p=3049"},"modified":"2023-04-22T05:50:02","modified_gmt":"2023-04-22T05:50:02","slug":"trimethoprim-sulfamethoxazole","status":"publish","type":"product","link":"https:\/\/medshop4u.com\/index.php\/product\/trimethoprim-sulfamethoxazole\/","title":{"rendered":"Trimethoprim &#038; Sulfamethoxazole"},"content":{"rendered":"<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">Average Delivery Time<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>10 to 14 days express shipping &#8211; or 3 to 4 weeks for regular shipping. | Medshop4u Online Pharmacy.<\/p>\n<\/div>\n<\/div>\n<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">Minimum Amount to Buy<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>You need to add Minimum 80$ Amount to your card | Medshop4u Online Pharmacy.<\/p>\n<\/div>\n<\/div>\n<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">Lowest price Guaranteed<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>We are offering the best costs on the web be that as it may on the off chance that you discover a site that beats our costs we will top that with another 5% to learn all the more Please Contact us | Medshop4u Online Pharmacy.<\/p>\n<\/div>\n<\/div>\n<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">How does Generic of Bactrim, Cotrim, Septra work?<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>Timethoprim Sulfamethoxazole inhibits the conversion of para amino benzoic acid (PABA) to dihydrofolate (DHFA) by inhibiting folate synthetase enzyme. Trimethoprim inhibits bacterial dihydrofolate reductase and blocks the conversion of dihydrofolate (DHFA) to tetra hydro folate (THFA). Thus Bactrim causes a sequential block of folate metabolism in bacteria.<\/p>\n<\/div>\n<\/div>\n<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">Side effects of Sulfamethoxazole and Trimethoprim<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>&nbsp;<\/p>\n<p>The common side effects reported with Bactrim are nausea, vomiting, anorexia, rash and urticaria, agranulocytosis, aplastic anemia, thrombocytopenia, hepatitis, elevation of serum transaminase and bilirubin, renal failure, interstitial nephritis, toxic nephrosis with oliguria and anuria, hyperkalemia, convulsions, peripheral neuritis, cough, shortness of breath and pulmonary infiltrates, weakness, fatigue and insomnia.<\/p>\n<\/div>\n<\/div>\n<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">Guidelines before using Sulfamethoxazole<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>Bactrim is not recommended in infants below the age of 2 months. Bactrim should be used with caution in patients who are taking thiazide diuretics as it can increase the incidence of thrombocytopenia with purpura. The combination of Sulfamethoxazole and Trimethoprim should be used carefully along with anticoagulant warfarin as it can prolong the prothrombin time. The serum digoxin levels should be monitored when given along with Bactrim. Bactrim should be given with caution in patients with renal or hepatic dysfunction, folate deficiency or bronchial asthma. Bactrim potentiates the effect of oral hypoglycemics in diabetic patients. Bactrim should not be administered in pregnant woman and nursing mothers as sulfamethoxazole and trimethoprim interfere with folic acid metabolism.<\/p>\n<\/div>\n<\/div>\n<div class=\"_6s2bg fggS- cell\">\n<h2 class=\"Text2446266173__root Text2446266173---typography-11-runningText Text2446266173---priority-7-primary s8gg2 _149OH InfoSectionTitle3095652555__root\" aria-hidden=\"false\" data-hook=\"info-section-title\">common dosages of Sulfamethoxazole and Trimethopri<\/h2>\n<div class=\"WncCi\" data-hook=\"info-section-description\">\n<p>The recommended starting dosage of Bactrim in adults for urinary tract infection and acute exacerbations of chronic bronchitis is 2 Bactrim tablets every 12 hours for 10 to 14 days. The recommended dose for children with urinary tract infections is 40 mg\/kg sulfamethoxazole and 8 mg\/kg trimethoprim given in two divided doses every 12 hours for 10 days. The recommended dosage for patients Pneumocystis carinii pneumonia is 75 to 100 mg\/kg sulfamethoxazole and 15 to 20 mg\/kg trimethoprim given in equally divided doses every 6 hours for 14 to 21 days. The recommended dose of Bactrim in traveller\u0080\u0099s diarrhea is 2 Bactrim tablets every 12 hours for 5 days.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<div class=\"H1AvN fggS- cell\">\n<section class=\"_2RbVQ\" data-hook=\"description-wrapper\">\n<div class=\"_3nbVj\">\n<div class=\"_3cRjW\" data-hook=\"content-wrapper\">\n<p>Sulfamethoxazole and\u00a0<strong>Trimethoprim<\/strong>\u00a0is an intermediate acing sulfonamide. The oral absorption of Sulfamethoxazole is slow. Sulfamethoxazole is the preferred compound for combining with Trimethoprim as both have similar half-life. Trimethoprim is a diaminopyrimidine. The fixed dose combination of Sulfamethoxazole and Trimethoprim is known as Cotrimoxazole. Sulfamethoxazole and Trimethoprim are bacteriostatic individually and become bactericidal when combined together. Trimethoprim has larger volume of distribution and attains lower plasma concentrations. Hence an optimum synergy is exhibited at a concentration ratio of Sulfamethoxazole 20: Trimethoprim 1. Trimethoprim enters blood brain barrier and placenta. You can\u00a0buy Trimethoprim Sulfamethoxazole here<\/p>\n<\/div>\n<\/div>\n<\/section>\n<\/div>\n<div class=\"_2-GPA fggS- cell\">\n<div dir=\"ltr\">\n<div class=\"_6s2bg fggS- cell\"><\/div>\n<\/div>\n<\/div>\n","protected":false},"featured_media":3124,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[212],"product_tag":[],"class_list":{"0":"post-3049","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-others","9":"instock","10":"sale","11":"taxable","12":"shipping-taxable","13":"purchasable","14":"product-type-variable"},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/product\/3049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/comments?post=3049"}],"version-history":[{"count":0,"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/product\/3049\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/media\/3124"}],"wp:attachment":[{"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/media?parent=3049"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=3049"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=3049"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medshop4u.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=3049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}