The common side effects reported with Anastrozole are flu syndrome, fever, malaise, neck pain, infection, hypertension, anemia, alkaline phosphatase increased, weight loss, pathological fracture, somnolence, confusion, insomnia, anxiety, nervousness, sinusitis, bronchitis, urinary tract infection and breast pain.

Anastrozole can be taken without regard of food. Arimidex and estrogen containing therapies should not be administered together as it can affect their pharmacological action. Anastrozole is contraindicated in women with pre-existing heart diseases. Arimidex should not be given to premenopausal women. Arimidex can cause harm to the fetus when taken during pregnancy. Anastrozole can cause some allergic reactions like swelling of lips, mouth or throat. There are chances of bone fractures during treatment with Anastrozole as it causes a loss in mineral content of bones. The Anastrozole treatment can cause an increase in cholesterol levels. It is advised to avoid taking Tamoxifen and Arimidex together. There is no need of dose adjustment in patients with renal or hepatic impairment.

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Anastrozole is a potent and selective aromatase enzyme inhibitor. Anastrozole inhibits the conversion of adrenal androgens to estrogen. . Arimidex lowers the amount of estradiol and thus prevent the progression of breast cancer.

The recommended starting dose of Arimidex is 1mg tablet taken once daily. Arimidex is prescribed for a period of five years. Arimidex should be continued until tumor progression when used to treat advanced breast cancer.