No major side effects have been reported with the use of Dapoxetine . Some of the common side effects observed are headache, dizziness, nausea, diarrhea, insomnia and fatigue. The symptoms occur with the first 3 hours of dosing and are not a cause of concern.

Dapoxetine is an orally administered drug. It can be used in men falling in the age group of 18-64 years. It is recommended to take the full tablet with a glass of water rather than chewing or biting it. Dapoxetine can cause dizziness and the patient should avoid activities that require alertness after taking Dapoxetine pills. Dapoxetine drug should be used with caution in people suffering from renal impairment and is contraindicated in patients suffering from hepatic impairment. It should not be used with other SSRI drugs. Dapoxetine should not be used by pregnant women, lactating mothers and children under the age of 18 years.

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It is believed that Dapoxetine works by inhibiting the neuronal reuptake of serotonin. This further potentiates the action of neurotransmitter at both pre and postsynaptic receptors. Ejaculation in humans is mediated by sympathetic nervous system. The inhibitory influence of Dapoxetine on the ejaculatory expulsion reflex system in the brain prevents premature ejaculation.

The recommended dosage is 30 mg tablet, taken on a need basis about 1 to 3 hours prior to sexual intercourse. It can be increased to 60 mg if response to 30 mg tablet is not satisfactory. The dosing frequency is once in 24 hours.