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Penile erection during sexual stimulation is caused by increased blood flow into the penile arteries. To ensure increased blood flow the muscles should be relaxed. A compound called as cGMP enables this relaxation. An enzyme called phosphodiesterase type 5 (PDE5) prevents the synthesis of cGMP, thereby not allowing the muscles to smoothen and relax, which results in erectile dysfunction. It acts on this enzyme and inhibits its action; thereby enabling the synthesis of cGMP and allowing increased blood supply to penile arteries. This medication is approved by FDA. Due to the longer duration of action, which is up to about 36 hours, it has earned the name as a €œweekend pill€.

The common side effects reported during clinical trials are headache, muscle aches, back pain and congested nose. Almost all of these symptoms disappear within 48 hours.

This is a need based pill and should be taken only when you plan to indulge in sexual activity. The drug should be taken only by adult men and should not be taken by males below 18 years of age. It should not be consumed along with alcohol as it can produce some adverse effects. It can be taken along with food or on an empty stomach. However heavy food intake can slow down the action of the drug. Patients consuming nitrate-based drugs should not consume this medication as the reaction between a nitrate-based drug and this can prove fatal.

This medication is available in dosages of 5 mg, 10 mg and 20 mg tablets. Recommended dosage is 10 mg tabled prior to sexual activity, which can be increased to 20 mg or decreased to 5 mg depending on the effect of the drug on the individual.