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Atomoxetine is a selective serotonin reuptake inhibitor (SSRI). Strattera causes selective inhibition of the pre-synaptic norepinephrine transporter.

The common side effects reported with Strattera are palpitation, dry mouth, nausea, constipation, abdominal pain, vomiting, dyspepsia, fatigue, chills, weight decrease, decreased apetite, dizziness, somnolence, insomnia, decreased libido, sleep disorder, rash, dysuria and erectile dysfunction.

Strattera can be taken with or without food. The dose of Strattera should be reduced in patients with hepatic or renal dysfunction. Atomoxetine when co-administered with monoamine oxidase inhibitor (MAOI) can cause serious fatal reactions like hyperthermia, rigidity, myoclonus and autonomic instability. Strattera should be used cautiously with pressor agents like dopamine and dobutamine. Strattera should be administered carefully with albuterol as action of albuterol on the cardiovascular system can be potentiated resulting in increases in heart rate and blood pressure. Patients should be instructed to exercise caution when driving a car or operating hazardous machinery. If it is an absolute must to take Atomoxetine during pregnancy, it should be administered under the supervision of a medical practitioner.

The recommended starting dosage of Strattera should be initiated at a total daily dose of 0.5 mg/kg and increased after a minimum of 3 days to a target total daily dose of 1.2 mg/kg. Strattera should be administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening.