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Isofair-10 (Isotretinoin) works by decreasing sebum production. The presence of high amounts of sebum can lead to severe acne.

Isofair-10 (Isotretinoin) should be taken along with food. The patient should be advised to avoid taking supplements containing vitamin A as Isotretinoin is a retinoid. The concomitant administration of Isotretinoin and tetracycline should be avoided as it can cause benign intracranial hypertension. The progesterone containing mini pills may be an inadequate method of contraception during Isofair-10 therapy.  Hence female patients of child-bearing age should be advised to take additional contraceptive methods while taking Isofair-10e tablets. The co-administration of systemic corticosteroids and Isotretinoin can cause osteoporosis. The patient should be advised not to donate blood during Isofair-10 treatment and within one month of discontinuing the treatment. Isotretinoin should never be administered to pregnant women and nursing mothers as it can cause fetal death. Isotretinoin should not be given to pediatric patients below the age of 12.

The recommended dose for Isofair-10 is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks.

The common side effects reported with Isotretinoin are allergic reactions, edema, fatigue, lymphadenopathy, weight loss, palpitation, tachycardia, vascular thrombotic disease, stroke, hypertriglyceridemia, alterations in blood sugar levels, inflammatory bowel disease, hepatitis, pancreatitis, bleeding and inflammation of the gums, colitis, esophagitis/esophageal ulceration, ileitis, nausea, skeletal hyperostosis, calcification of tendons and ligaments, premature epiphyseal closure, decreases in bone mineral density, back pain, myalgia, arthralgia, depression, psychosis, aggression and violent behaviors.