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Itraconazole or Sporanox can cause side effects such as nausea, abdominal discomfort, allergy like rash, water retention, and even hepatitis.

Sporanox tablets should be taken only after a full meal. It may take a few to several months for the treatment to be complete. During this period, the intake of Sporanox should be evenly spaced and at regular intervals. Patients suffering from congestive heart failure should not take Sporanox. Pregnant women as well as women planning to get pregnant should not be administered this drug. Sporanox is also known to interact with drugs such as cisapride, pimozide, quinidine, dofetilide, or levacetylmethadol (levomethadyl) to produce adverse effects. Hence Sporanox should not be co-administered with these drugs.