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The common side effects reported with Clotrimazole are burning, itching, pain in vagina or urinary opening and abdominal cramps. The rare and serious side effects include allergic reaction manifested as rashes, itching, swelling, severe dizziness and trouble in breathing.

Clotrimazole is applied on the affected and surrounding area, which is cleaned and dried. Lotrimin is to be applied on the skin as prescribed for the full treatment time to kill yeasts completely even if the symptoms are relieved. You should continue application of the medicine for the prescribed time to avoid ineffective treatment and re-infection. Clotrimazole should be used only for vulvar itching due to yeast infection. Lotrimin cream can be continued during your menstruation. Clotrimazole can reduce the effectiveness of birth control methods like vaginal cream, condoms, diaphragms and vaginal spermicides. Lotrimin should not be applied on eyes, nostrils or mouth. It is not advisable to apply this drug during pregnancy. Antifungal treatment using Lotrimin can be initiated after childbirth.