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The common side effects reported with Lopressor are tiredness, dizziness, shortness of breath, bradycardia, diarrhea, nausea, dry mouth, gastric pain, flatulence, heart burn, pruritis and rash.
Reserpine can potentiate postural hypotension in patients on Lopressor therapy. Metoprolol and clonidine should never be adminitered together as it can cause rebound hypertension. Metoprolol is safe in asthmatics. Lopressor should be used with caution in patients with hepatic dysfunction. Metoprolol is not safe for pregnant women, nursing mothers and pediatric patients. Lopressor is contraindicated in sinus bradycardia, sick sinus syndrome and second or third degree heart block. The patient should be advised to avoid activities that require alertness. The patient should be cautioned of cold hands and feet during Metoprolol treatment due to reduced blood flow.