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The common side effects reported with Montelukast are asthenia, fatigue, fever, pain, abdominal trauma, dyspepsia, gastroenteritis, dizziness, headache, nasal congestion, cough, influenza and rash.

Montelukast should be taken once daily in evening. Singulair is not indicated for use in the reversal of bronchospasm in acute asthma attacks. Patients suffering from exacerbations of asthma after exercise should be advised to keep a short-acting inhaled β-agonist as a rescue medication. Montelukast should not be abruptly substituted for inhaled or oral corticosteroids. Singulair can cause neuropsychiatric events in adults and pediatric patients. The patients should be advised to continue Montelukast for the minimum time indicated even if they are asymptomatic. Montelukast should not be given to pregnant women and nursing mothers. If it is an absolute must to take Singulair during pregnancy, it should be administered under the supervision of a medical practitioner.