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The common side effects reported with Reboxetine during clinical trials are insomnia, increased sweating, dizziness, hypotension, paraesthesia, impotence, urinary tract infection, dysuria, dry mouth, constipation, insomnia, tachycardia and vertigo.

The use of Reboxetine is not recommended in patients who have hypersensitivity towards this compound, seizure disorders, pregnancy, lactation and children. It is not advisable to consume the Reboxetine during pregnancy. If it is an absolute must to take Edronax during pregnancy, it should be administered under the supervision of a medical practitioner. The dose of Edronax should be adjusted in patients with renal impairment, hepatic insufficiencies and in elderly patients because of increased plasma levels and half lives of drug. Patients should use operating machinery carefully and avoid driving during the course of Reboxetine treatment since it is known to cause drowsiness.