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How does Cimetidine / Generic of Tagamet work?
Cimetidine is a selective H2 blocker. Tagamet blocks histamine induced gastric secretion.
Side effects of Cimetidine / Generic of Tagamet
The common side effects reported with Tagamet are diarrhea, headaches, mental confusion, agitation, psychosis, depression, anxiety, hallucinations, disorientation, impotence, agranulocytosis, aplastic anemia, bradycardia, tachycardia, A-V heart block, arthralgia, myalgia and exacerbation of joint symptoms.
Guidelines before using Cimetidine
The co-administration of warfarin and Tagamet can alter the prothrombin time. Cimetidine is not administered in pediatric patients below the age of 16. It is not advisable to consume the Tagamet during pregnancy and lactation. Tagamet should not be given along with Atazanavir, herbal products and azole antifungals due to serious drug interactions.
What are the common dosages of Cimetidine
The recommended dosage of Tagamet in gastric and duodenal ulcers for adults is 800mg once daily at bedtime or 300 mg four times a day with meals. The recommended adult oral dosage for the treatment of erosive esophagitis is 1600 mg daily in divided doses.