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The common side effects reported with Plendil are peripheral edema, hypotension, asthenia, palpitation, nausea, dyspepsia, constipation, head ache, dizziness, upper respiratory tract infection, coughing, sneezing, rash and flushing.

It is advised to swallow the tablet whole and not crushed or chewed. The dose of Plendil needs to be adjusted in patients with hepatic impairment and in elderly patients by monitoring blood pressure response. Felodipine when taken along with other calcium channel blockers can precipitate hypotension. You can develop peripheral edema during Plendil treatment. You should not take Plendil along with grape juice. It is not advisable to consume Felodipine during pregnancy. If it is an absolute must to take Plendil during pregnancy, it should be administered under the supervision of a medical practitioner. Avoid use of Felodipine when you are breast-feeding as it gets excreted in the breast milk.