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The common side effects reported with Relafen are diarrhea, dyspepsia, abdominal pain, constipation, flatulence, nausea, positive stool guaiac, dry mouth, gastritis, stomatitis, vomiting, dizziness, headache, fatigue, increased sweating, insomnia, nervousness, somnolence, pruritus, rash, tinnitus and edema.
Relafen diminishes antihypertensive impact of Angiotensin Converting Enzymes. Nabumetone can lessen the diuretic and antihypertensive impacts of furosemide and thiazide diuretics. The attending organization of Relafen and lithium can cause lithium poisonous quality. Alert ought to be utilized when Nabumetone is controlled correspondingly with methotrexate. The corresponding organization of Relafen and warfarin type anticoagulants can cause with deadly gastrointestinal dying. Nabumetone isn’t utilized as an option in contrast to corticosteroids or to treat corticosteroid deficiency. Patients ought to be educated regarding signs and manifestations of hepatotoxicity, which can happen during Relafen treatment. Relafen can cause weakness because of liquid maintenance and GI blood misfortune. The utilization of Relafen causes an expanded danger of cardiovascular thrombotic occasions, myocardial localized necrosis, and stroke. Relafen can cause genuine gastrointestinal occasions including dying, ulceration, and aperture of the stomach, small digestive tract or internal organ. Relafen ought to be kept away from in late pregnancy as it can cause the untimely conclusion of the ductus arteriosus. Relafen isn’t prescribed for nursing moms. Relafen can cause genuine skin reactions, for example, shed dermatitis.