Ranitidine is a selective H2 antihistaminic. This drug blocks gastric secretion, cardiac stimulation, and bronchial relaxation. Zantac is also used in the treatment of gastric and duodenal ulcers, hypersecretory conditions like Zollinger-Ellison syndrome and systemic mastocytosis and erosive esophagitis. Zantac is highly selective in action. Zantac has no effect on H1 mediated responses or on action of other transmitters or autocoids. It blocks all the phases of gastric secretion. The secretory responses to histamine are attenuated. Zantac amplifies the responses to secretagogues. It reduces the volume of acid, pepsin content and intrinsic factor secretion. This does not interfere with vitamin B12 absorption. You can easily buy Ranitidine here
The common side effects reported with Ranitidine are tachycardia, bradycardia, atrioventricular block, and premature ventricular beats, constipation, diarrhea, nausea, vomiting, abdominal discomfort, leukopenia, granulocytopenia, and thrombocytopenia, rash, malaise, dizziness, somnolence, insomnia, and vertigo.
Guidelines
The co-administration of warfarin and Zantac can alter the prothrombin time. The dose of Zantac should be reduced in patients with renal or hepatic dysfunction. The use of Zantac is contraindicated in patients with a history of acute porphyria. It is not advisable to consume the Zantac during pregnancy and lactation. Ranitidine should not be given along with Atazanavir and Delavirdine as tbheir absorption is interferred due to increased gastic pH by this drug.
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How does Ranitidine / Generic of Zantac work?
Ranitidine is a selective H2 blocker. This drug blocks histamine induced gastric secretion.
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