The common side effects reported with Ranitidine are tachycardia, bradycardia, atrioventricular block, and premature ventricular beats, constipation, diarrhea, nausea, vomiting, abdominal discomfort, leukopenia, granulocytopenia, and thrombocytopenia, rash, malaise, dizziness, somnolence, insomnia, and vertigo.

The co-administration of warfarin and Zantac can alter the prothrombin time. The dose of Zantac should be reduced in patients with renal or hepatic dysfunction. The use of Zantac is contraindicated in patients with a history of acute porphyria. It is not advisable to consume the Zantac during pregnancy and lactation. Ranitidine should not be given along with Atazanavir and Delavirdine as tbheir absorption is interferred due to increased gastic pH by this drug.

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Ranitidine is a selective H2 blocker. This drug blocks histamine induced gastric secretion.