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Parlodel has greater action on D2 receptors. Parlodel acts as partial agonist or antagonist of D1 receptor at certain dopamine sites in brain.

The common side effects reported with Bromocriptine nausea, head ache, dizziness, fatigue, lightheadedness, vomiting, abdominal cramps, nasal congestion, nausea, diarrhea, drowsiness, hypotension, anorexia, dry mouth, nasal stuffiness, indigestion, dyspepsia, abnormal involuntary movements, hallucinations, confusion, “on-off” phenomenon, asthenia, abdominal discomfort, visual disturbance, ataxia, insomnia, depression, hypotension, shortness of breath and vertigo.

Parlodel causes hypotension due to central suppression of postural reflexes and weak peripheral ά blockade. Parlodel is not recommended for use in children below the age of 8. Bromocriptine contraindicated in patients with renal or hepatic disease. Bromocriptine should be used with caution in patients with a history of psychosis and cardiovascular disease. Parlodel should not be administered to patients having galactose intolerance, the severe lactase deficiency or glucose-galactose malabsorption. Bromocriptine cause cold-sensitive digital vasospasm in acromegaly patients. The use of Bromocriptine in higher doses can cause confusion and mental disturbances. Parlodel should be administered with caution in patients with myocardial infarction. It is not advisable to consume the Parlodel during pregnancy and lactation.

The recommended dosage of Parlodel is 2.5-15mg daily. The dose of Parlodel in children is 2.5-10mg daily.