Rivastigmine is a carbamate derivative of physostigmine that inhibits both acetyl choline esterase and butyl choline esterase. Exelon is more selective for G1 form of acetyl choline esterase. Acetyl choline esterase predominates in certain areas of brain. Rivastigmine Tartrateis highly lipid soluble and can easily enter brain. Rivastigmine Tartrateaugments cholinergic transmission in brain with mild peripheral effect. The carbamyl residue of Rivastigmine Tartrateinhibits Acetyl choline esterase for up to 10hrs. You can now easily buy Rivastigmine here


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How does Rivastigmine / Generic of Exelon work?

Exelon enhances cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by cholinesterase enzyme.


Side effects of Rivastigmine / Generic of Exelon

The common side effects reported with Exelon are accidental trauma, fever, edema, allergy, hot flushes, rigors, hypotension, postural hypotension, cardiac failure, abnormal gait, ataxia, paresthesia, convulsions f,ecal incontinence, gastritis, tinnitus, atrial fibrillation, bradycardia, palpitation, dehydration, hypokalemia, arthritis, leg cramps, myalgia, angina pectoris and myocardial infarction.


Guidelines before using Rivastigmine / Exelon

Exelon should not be administered along with anticholinergic medications as Rivastigmine Tartrateinterferes with their function. The co-administration of Rivastigmine Tartrateand succinylcholine, neuromuscular blocking agents and bethanechol should be avoided because of synergistic effects. It is not advisable to consume the Exelon drug during pregnancy. If it is an absolute must to take Exelon during pregnancy, it should be administered under the supervision of a medical practitioner. Exelon is not administered to nursing mothers or in pediatric patients.


What are the common dosages of Generic Exelon?

The starting dose of Exelon is 1.5 mg twice a day. The dose may be increased to 3 mg BID after 2weeks, if it is well tolerated by the patient. The subsequent increases to 4.5 mg BID and 6 mg BID should be done after a minimum of 2 weeks at the previous dose. The maximum dose of Rivastigmine Tartrateis 12mg/day.



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